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Vulnerability record · CVE-2017-1000206 · published 17 November 2017

CVE-2017-1000206: Htslib memory buffer overflow vulnerability

HHtslib · Htslib

samtools htslib library version 1.4.0 and earlier is vulnerable to buffer overflow in the CRAM rANS codec resulting in potential arbitrary code execution

9.8 CVSS 3.0 Critical EPSS 2.0% · top 20.6% CWE-119 · Memory buffer overflow
9.8CVSS 3.0 base score, v2 7.5
2.0%EPSS exploitation probability, 30 days
NoNot in CISA KEV
1Affected product versions listed by NVD
2References
17 Jun 2026Last modified by NVD

Description

samtools htslib library version 1.4.0 and earlier is vulnerable to buffer overflow in the CRAM rANS codec resulting in potential arbitrary code execution

CVSS:3.0/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H

Affected products

1 vulnerable configurations from NVD's CPE data, grouped by vendor and product.

References

LinkTags
https://github.com/samtools/htslib/blob/1.4.1/NEWS Release NotesThird Party Advisory
https://github.com/samtools/htslib/blob/1.4.1/NEWS Release NotesThird Party Advisory

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Related vulnerabilities

Same products first, then exploited flaws of the same weakness class.

9.8CVE-2018-13845Htslib out-of-bounds read vulnerabilityAn issue has been found in HTSlib 1.8. It is a buffer over-read in sam_parse1 in sam.c.EPSS 1.6%8.8CVE-2026-31968Htslib stack-based buffer overflow vulnerabilityHTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a…EPSS 0.52%8.8CVE-2026-31963Htslib heap-based buffer overflow vulnerabilityHTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. As one…EPSS 0.52%8.8CVE-2026-31962Htslib heap-based buffer overflow vulnerabilityHTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. While …EPSS 0.59%8.8CVE-2020-36403Htslib out-of-bounds write vulnerabilityHTSlib through 1.10.2 allows out-of-bounds write access in vcf_parse_format (called from vcf_parse and vcf_read).EPSS 1.6%7.5CVE-2018-13843Htslib vulnerabilityAn issue has been found in HTSlib 1.8. It is a memory leak in bgzf_getline in bgzf.c. NOTE: the software maintainer's position is that the "failure t…EPSS 1.5%7.5CVE-2018-13844Htslib memory leak vulnerabilityAn issue has been found in HTSlib 1.8. It is a memory leak in fai_read in faidx.c. NOTE: This has been disputed with the assertion that this vulnerab…EPSS 1.4%7.1CVE-2026-31971Htslib stack-based buffer overflow vulnerabilityHTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a…EPSS 0.52%

Source: NIST National Vulnerability Database (record CVE-2017-1000206), CISA KEV, FIRST EPSS (scores of 2026-09-26). This page is refreshed as NVD updates the record.