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Vulnerability record · CVE-2026-100845 · published 27 September 2026

CVE-2026-100845: Deserialization of untrusted data vulnerability

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

8.5 CVSS 4.0 High CWE-502 · Deserialization of untrusted data Received
8.5CVSS 4.0 base score
—EPSS exploitation probability, 30 days
NoNot in CISA KEV
0Affected product versions listed by NVD
2References
27 Sep 2026Last modified by NVD

Description

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

CVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:

References

LinkTags
https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr
https://www.vulncheck.com/advisories/monai-before-1.6.0-remote-code-execution-via-numpyreader

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Source: NIST National Vulnerability Database (record CVE-2026-100845), CISA KEV, FIRST EPSS. This page is refreshed as NVD updates the record.