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Vulnerability record · CVE-2025-54808 · published 23 October 2025

CVE-2025-54808: Insufficiently protected credentials vulnerability

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 stores authentication tokens in a file located in the system's temporary directory (/tmp) on the host machine. This directory is typically world-readable, allowing any local user or application to access the token. If the token is leaked (e.g., via malware infection or other local exploit), and remote access is enabled, it can be used to establish unauthorized remote connections to the sequencer. Remote access must be enabled for remote exploitation to succeed. This may occur either because the user has enabled remote access for legitimate operational reasons or because malware with elevated privileges (e.g., sudo access) enables it without user consent. This vulnerability can be chained with remote access capabilities to generate a developer token from a remote device. Developer tokens can be created with arbitrary expiration dates, enabling persistent access to the sequencer and bypassing standard authentication mechanisms.

7.3 CVSS 4.0 High EPSS 0.16% · top 95.6% CWE-522 · Insufficiently protected credentials Deferred
7.3CVSS 4.0 base score
0.16%EPSS exploitation probability, 30 days
NoNot in CISA KEV
0Affected product versions listed by NVD
4References
17 Jun 2026Last modified by NVD

Description

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 stores authentication tokens in a file located in the system's temporary directory (/tmp) on the host machine. This directory is typically world-readable, allowing any local user or application to access the token. If the token is leaked (e.g., via malware infection or other local exploit), and remote access is enabled, it can be used to establish unauthorized remote connections to the sequencer. Remote access must be enabled for remote exploitation to succeed. This may occur either because the user has enabled remote access for legitimate operational reasons or because malware with elevated privileges (e.g., sudo access) enables it without user consent. This vulnerability can be chained with remote access capabilities to generate a developer token from a remote device. Developer tokens can be created with arbitrary expiration dates, enabling persistent access to the sequencer and bypassing standard authentication mechanisms.

CVSS:4.0/AV:L/AC:L/AT:P/PR:L/UI:N/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:

References

LinkTags
https://github.com/cisagov/CSAF/blob/develop/csaf_files/OT/white/2025/icsma-25-294-01.json
https://nanoporetech.com/about/contact
https://nanoporetech.com/software/
https://www.cisa.gov/news-events/ics-medical-advisories/icsma-25-294-01

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Source: NIST National Vulnerability Database (record CVE-2025-54808), CISA KEV, FIRST EPSS (scores of 2026-09-26). This page is refreshed as NVD updates the record.